Setting the Stage for Deep-Data Analysis and Innovation

“With great power comes great responsibility” – Ben Parker.

Ontario Brain Institute’s (OBI) researchers collect ‘deep data’ using scientific and clinical tools like behavioural tests, neuroimaging and genetics. By bringing these data together in Brain-CODE, we can develop a holistic approach to understanding brain disorders. A recent report, “Dementia Research and Care: Can Big Data Help?”, by the Organization for Economic Co-operation and Development (OECD), Ontario Brain Institute and the University of Toronto highlighted the potential of linking ‘deep data’ from basic and clinical research to ‘broad data’ from healthcare and population-level statistics to driving new discoveries and applications of research in healthcare and policy.

The question is how can we best link ‘deep’ research data and ‘broad’ health data to drive new discoveries and benefit people in their communities?

Continue reading “Setting the Stage for Deep-Data Analysis and Innovation”

Inventiveness Accelerates Drug Discovery Process- A smart shortcut to developing new drug treatments for Parkinson’s disease

It takes almost a decade and billions of dollars to develop a drug for brain disorders. Furthermore, 88% of those drugs fail clinical trials because of their lack of efficacy and safety1.  The entire process is not only daunting but very costly, in terms of time and money.

But, what if there was a way to accelerate the process? Continue reading “Inventiveness Accelerates Drug Discovery Process- A smart shortcut to developing new drug treatments for Parkinson’s disease”

Sharing Data For Better And More Efficient Science

By: Teige Bourke, Outreach Intern, Ontario Brain Institute

Brain disorders are not straightforward. Disorders like depression result from a complex interplay between an individual’s experiences and their biology. Understanding the underlying mechanisms requires a lot of information that can only be extracted through research that uses many different techniques with large groups of people. Continue reading “Sharing Data For Better And More Efficient Science”

Principles for Collective Research Acceleration

By: Suzanna Stevanoski, OBI Intern, Operations

Sharing data on a large-scale requires the creation of a highly sophisticated system, one that allows many researchers to connect, manage, protect, and standardize data. That’s why OBI is finding innovative ways to unite researchers in pooling their expertise and resources to achieve greater impact than they could have achieved in isolation. Continue reading “Principles for Collective Research Acceleration”

International Data Linkages For New Possibilities In Autism Research

OBI catalyzes the impact of brain research in Ontario by increasing collaboration among researchers, doctors, patients and their advocates, and industry partners. A key ingredient to collaboration is, of course, sharing.  At OBI, a cornerstone of effective research collaboration involves sharing large quantities of data. In order for this to be done effectively, it must be stored somewhere where it can be accessed and analyzed collectively. Continue reading “International Data Linkages For New Possibilities In Autism Research”

Brain-CODE’s Leadership

In this era of big data and analytics, organizations are looking for ways to make use of all the information available to facilitate innovation, decision making and operations. Big data analytics in health research has been an important topic for the past few years and making data more accessible to a larger number of researchers leads to more efficient research strategies and creates new opportunities for scientific discoveries. When scientists have the opportunity to collaborate and share data, the value of each of their work is maximized and can be built on collectively. Continue reading “Brain-CODE’s Leadership”

Joining Global Discussions on Data Sharing

In OBI’s goal to improve brain health, research data are one of the basic building blocks.  Data are assets that hold value because they can be shared, analysed, and reused in different ways to support new discoveries and reduce the loss of resources. One opportunity to reuse data and uncover new insights is the linking of routinely collected population and healthcare data, or ‘broad’ data, with ‘deep’ research data (e.g., imaging, genetics, etc.).  To harness data’s full potential, OBI has developed several initiatives including an informatics platform, an international workshop, and internships to address linking and sharing data in new ways. Continue reading “Joining Global Discussions on Data Sharing”